Reproductive, cytological and biochemical toxicity of fenugreek in male Swiss albino mice
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Reproductive, cytological and biochemical toxicity of Yohimbe in male Swiss albino mice.
AIM To study the effect of Corynanthe Yohimbe (Yohimbe) on germ cells in Swiss albino mice. METHODS Adult male mice were orally (gavage) treated with different doses (188, 375 and 750 mg/[kg x day]) of aqueous suspension of Yohimbe for 90 days. The following parameters were evaluated: (i) reproductive organ weight, (ii) motility and count of sperm, (iii) study on rate of pregnancy and mean im...
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St John’s Wort (SJW, Hypericum perforatum), a popular dietary supplement is immensely used in treating a broad range of psychiatric disorders. It is reported to possess both favorable and detrimental effects. Which are attributed to the active principles (hypericin and hyperforin) of SJW. Nevertheless, there is dearth of reports on toxicity of SJW. In view of the traditional significance of SJW...
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The java tea is significantly used in traditional medicine for its anti-allergic, antihypertensive, antiinflammatory and diuretic properties. The present study is designed to assess the effect of java tea after its chronic use on male reproduction, cytological and biochemical changes in Swiss albino mice. Java tea was administered orally at the doses 62.50, 125 and 250 mg/kg/day for 90 days. Hi...
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Background: This study has been undertaken to find out the possible radioprotective potential of the Alstonia scholaris extract (ASE). Materials and Methods: For experimental study, healthy Swiss albino male mice were selected from an inbred colony and divided in four groups. Group I (normal) did not receive any treatment. Group II was orally supplemented ASE once daily at the dose of ...
متن کاملArtesunate Induced Hepato-Toxicity and its Amelioration by Allium sativum in Swiss Albino Male Mice
The use of natural antioxidants as mitigating agents has become prevalent. Garlic (Allium sativum) is one such agent which has been proven to have antibacterial, antiseptic, antifungal, antiparasitic, anticoagulant and antitumor properties. The present investigation deals with the ameliorative effects of Allium sativum on the antimalarial drug induced hepato-toxicity. Artesunate is being used a...
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ژورنال
عنوان ژورنال: African Journal of Pharmacy and Pharmacology
سال: 2013
ISSN: 1996-0816
DOI: 10.5897/ajpp2013.3449